https://kongjianyang.r-universe.devRecent package updates in kongjianyangR-universehttps://github.com/kongjianyang.pnghttps://kongjianyang.r-universe.devTue, 28 Jul 2026 16:10:08 GMTxphdtangliang@gmail.com (Liang Tang)A complete workflow for large-scale, two-condition high-throughput drug screening (HTS). It compares drug sensitivity between any two experimental conditions - for example irradiated versus non-irradiated cells, cancer versus normal cell lines, or treated versus untreated samples - across many plates and experiments. The package covers the full pipeline: control-based normalisation, plate-level quality-control metrics (Z-factor, Z-prime, signal-to-background, signal-to-noise and strictly standardised mean difference), replicate-consistency checks, four-parameter logistic dose-response fitting with area under the curve (AUC) estimation, differential (delta) AUC scoring with within-plate standardisation, cut-off and sigma-based hit selection, and publication-ready heatmap, scatter and quality-control visualisations.https://github.com/r-universe/kongjianyang/actions/runs/36307046291Tue, 28 Jul 2026 16:10:08 GMTdiffHTS0.1.0successhttps://kongjianyang.r-universe.devhttps://github.com/cran/diffHTSdiffHTS.RmddiffHTS.htmlAnalysing a two-condition drug screen with diffHTS2026-07-28 16:10:082026-07-28 16:10:08